SimGlycan® Workflow

High Throughput Analysis of Reducing End Modified Glycans


Note: Presentation, Sample Data, and Resources are Mass spec vendor specific. To download, please click on the appropriate vendor icon first

SimGlycan analyzes mass spectrometry data for identification of reducing end modified glycans. The software supports analyzing glycan samples labeled with major fluorophore such as 2-Aminobenzamide (2-AB), 2-Aminobenzoic acid (2-AA), GlycoWorks RapiFluor-MS, etc..for the data generated by Direct infusion-, LC-, MALDI- MS/MS workflows. It reads the observed peaks, match those with theoretical ions of each candidate glycan and reports the candidate glycan structures in a ranked order using a proprietary scoring algorithm. The software can analyze up to 10,000 MS/MS spectra per high throughput search batch and the search results can be exported, along with glycan structures in an Excel file for easy sharing.

Key Features in the workflow:

  • Supports direct loading of raw data from Thermo Scientific native .raw file format
  • LC-MS peak detection and picking
  • High Throughput identification of glycans
  • MS/MS annotation
  • Portable report generation


customer service software technical support
Live Chat by Comm100