SimGlycan® Workflow

High Throughput Analyses of Permethylated Glycans


SimGlycan can analyze mass spectrometry data for identification Permethylated glycans. The software supports analyses of data generated by Direct infusion-, LC-, MALDI- MS and MS/MS workflows. It reads the observed peaks, match those with theoretical ions of each candidate glycan and reports the candidate glycan structures in a ranked order using a proprietary scoring algorithm. The software can analyze up to 10,000 MS/MS spectra per high throughput search batch and the search results can be exported, along with glycan structures in an Excel file for easy sharing.

Key Features in the workflow:

  • Supports direct loading of native data files of all major mass spectrometry vendors
  • LC-MS peak detection and picking
  • High Throughput identification of glycans
  • MS/MS annotation
  • Portable report generation


Resources

Literature

MultiNotch MS3 Approach for Relative Quantification of N-Glycans Using Multiplexed Carbonyl-Reactive Isobaric Tags...

Creating a Mass Spectral Reference Library for Oligosaccharides in Human Milk...

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Posters

Automated and Rapid Characterization of Low-Molecular-Weight Heparin Oligosaccharides Using TripleTOF 5600 Mass Spectrometer...

SimGlycan: Informatics Support for Automated Characterization of Low-Molecular-Weight...

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Application Notes

A Unique Workflow for Glycoprotein Characterization from Sample Preparation to MS/MS Spectral...

SimGlycan Software: A New Predictive Carbohydrate Analysis Tool for MS/MS Data Automated Data Interpretation for Glycan Characterization...

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Webinar

Automating mass spectrometry based glycan identification and quantitation using SimGlycan software

Use SimGlycan for glycan and glycopeptide analysis, glycan structure prediction, glycosylation analysis...

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