PREMIER Biosoft International releases SimLipid with support for structural elucidation
Palo Alto, California – March 22, 2011, PREMIER Biosoft International today announced the release of the second version of its innovative product, SimLipid, with support for MS/MS data analysis and correction of peak intensities for MS lipid profiles with overlapping isotopes. These new features of SimLipid enable speedy analysis of lipid mass spectrometric data for characterizing lipids and provide a platform for quantitative analysis of lipids present in a sample mixtures.
SimLipid profiles lipids by matching the experimental MS spectra with its own comprehensive, robust and annotated database, consisting of 8 lipid categories and 21905 lipid species. SimLipid enables users to perform MS/MS data analysis of Glycerophospholipids, Glycerolipids, Prenol Lipids and Saccharolipids with ease. The resulting structures are plotted in 2D layout and sorted based on an innovating ranking algorithm that maps the degree of proximity of theoretical lipids with experimental data. High Resolution Accurate Mass (HRAM) data with error tolerance between 1-20 ppm can also be analyzed, improving the accuracy of prediction.
SimLipid provides a high throughput module to streamline isotope percentage calculations for MS lipid profiles and correct the experimental peak intensities to remove lipids with isotopic overlaps, assisting in accurate quatitation of lipids from biological mixtures.
"The advancement in lipidomics has largely been inhibited by the lack of analysis tools. We developed SimLipid for systems-level analysis of lipids, placing a powerful tool in the hands of researchers working in the area of biomedical research in general, and drug and biomarker development in particular." said Kay Brown, V.P. Business Development and Marketing.
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