ProteoIQ provides an easy-to-use and intuitive solution for combining results from popular database search engines to validate protein identifications, compare and quantify protein expression across 100's of samples in a single project. It supports all popular forms of peptide and protein quantification such as label free, isotopic and isobaric tag based quantification workflows. With label free quantification workflows, you can quantify proteins via Area Under Curve (AUC) from extracted ion chromatograms (XIC) of every detected peak, from Precursor Intensity of identified peptides from the MS/MS spectra or from Spectral Counting (SC) of identified MS/MS spectra. Further, ProteoIQ allows you to quantify protein expression using iTRAQ, TMT, SILAC, ICAT or any other isobaric or isotopic labels.
ProteoIQ® is a comprehensive suite to validate and quantify proteins by combining results from popular mass spectrometry platforms and database search engines. With dynamic extracted ion chromatogram plots, the ability to view every MS spectra at any time point and the ability to manually select a peak area, ProteoIQ® provides the ultimate level of control.
ProteoIQ® provides a completely customizable interface to support any form of biological annotation. You can easily compare protein quantitative results in relation to biological pathways, protein localization, protein function, or even compare to transcript abundance. Every protein identification in ProteoIQ® can be linked to any external or internal knowledge database. Custom links are provided to GenBank, UniProt, IPI, and SwissProt databases or even an in-house LIMS.