SimGlycan analyzes mass spectrometry data for identification of reducing end modified glycans. The software supports analyzing glycan samples labeled with major fluorophore such as 2-Aminobenzamide (2-AB), 2-Aminobenzoic acid (2-AA), GlycoWorks RapiFluor-MS, etc. for the data generated by Direct infusion-, LC-, MALDI- MS/MS workflows. It reads the observed peaks, match those with theoretical ions of each candidate glycan and reports the candidate glycan structures in a ranked order using a proprietary scoring algorithm. The software can analyze up to 10,000 MS/MS spectra per high throughput search batch and the search results can be exported, along with glycan structures in an Excel file for easy sharing.
Key Features in the workflow: