High Throughput Analysis of Permethylated Glycans

SimGlycan can analyze mass spectrometry data for identification Permethylated glycans. The software supports analysis of data generated by Direct infusion-, LC-, MALDI- MS and MS/MS workflows. It reads the observed peaks, match those with theoretical ions of each candidate glycan and reports the candidate glycan structures in a ranked order using a proprietary scoring algorithm. The software can analyze up to 10,000 MS/MS spectra per high throughput search batch and the search results can be exported, along with glycan structures in an Excel file for easy sharing.

Key Features in the workflow:

• Supports direct loading of native data files of all major mass spectrometry vendors
• LC-MS peak detection and picking
• High Throughput identification of glycans
• MS/MS annotation
• Portable report generation